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Learning Objectives:

  • Examine the connection between the oral and gut microbiomes, including how they interact with one another.

  • Explain how Porphyromonas gingivalis may contribute to dysbiosis in the gut microbiota

  • Analyze how oral inflammation plays a contributory role in the worsening of inflammatory bowel disease and Crohn's disease.

  • Assess the research associating periodontitis with both colon cancer and pancreatic cancer

  • Discuss how periodontal therapy and proper oral hygiene might influence gastrointestinal health

The first segment discusses the pathway through which oral bacteria infiltrate the intestines, also impacting gut health.  This segment gives particular focus to the potential impact of Porphyromonas gingivalis, a prevalent periodontal pathogen, in driving dysbiosis within the gut microbiota and its subsequent implications. 

The second section critically analyzes the contributory role of oral inflammation in the exacerbation of inflammatory bowel disease (IBD) and Crohn's disease, shedding light on the potential mechanisms involved. In addition, we explore the emerging research exploring the association between periodontitis and colon cancer as well as pancreatic cancer. 

Finally, the course discusses the potential influence of periodontal therapy and maintaining proper oral hygiene on gastrointestinal health, offering insights into preventive strategies and therapeutic interventions for the enhancement of overall well-being. Participants will gain valuable knowledge essential for effective clinical practice and patient care.

This course explores the intricate relationship between the oral and gut microbiomes.  We investigate the route by which oral bacteria infiltrate the intestines, with a specific focus on the role Porphyromonas gingivalis has in the development of gut dysbiosis. Additionally, we discuss how oral inflammation exacerbates inflammatory bowel disease and Crohn's disease and explore potential links between periodontal disease, colon cancer, and pancreatic cancer. Furthermore, we emphasize the role of dental professionals in educating patients about the preventive potential of good oral hygiene in averting gut dysbiosis. 

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